CHEBI:45081 - pentamidine

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ChEBI Name pentamidine
ChEBI ID CHEBI:45081
Definition A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:45077, CHEBI:7976
Supplier Information
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Roles Classification
Biological Role(s): antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
trypanocidal drug
A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida.
NMDA receptor antagonist
Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs.
chemokine receptor 5 antagonist
An antogonist that blocks chemokine receptor 5 (CCR5).
EC 2.3.1.48 (histone acetyltransferase) inhibitor
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the function of histone acetyltransferase (EC 2.3.1.48).
calmodulin antagonist
An antagonist that interferes with the action of the calcium-binding messenger protein calmodulin.
S100 calcium-binding protein B inhibitor
Any inhibitor of S100 calcium-binding protein B.
xenobiotic
A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
Application(s): trypanocidal drug
A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida.
anti-inflammatory agent
Any compound that has anti-inflammatory effects.
Related Structures
pentamidine is a Conjugate Base of
pentamidinium(2+)
Mass : 342.43420
Formula : C19H26N4O2
64383
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