CHEBI:6701 - maytansine

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ChEBI Name maytansine
ChEBI ID CHEBI:6701
Definition An organic heterotetracyclic compound and 19-membered macrocyclic lactam antibiotic originally isolated from the Ethiopian shrub Maytenus serrata but also found in other Maytenus species. It exhibits cytotoxicity against many tumour cell lines.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Roles Classification
Biological Role(s): plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
tubulin modulator
Any substance that interacts with tubulin to inhibit or promote polymerisation of microtubules.
antimitotic
Any compound that inhibits cell division (mitosis).
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
Related Structures
maytansine is a Functional Parent of
mertansine
Mass : 738.28800
Formula : C35H48ClN3O10S
82755
maytansine is a Structural Derivative of
oxirane
Mass : 44.05256
Formula : C2H4O
27561
carbamic acid
Mass : 61.04006
Formula : CH3NO2
28616
alpha-amino acid
Mass : 74.05870
Formula : C2H4NO2R
33704
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