Ketcher 12191712422D 1   1.00000     0.00000     0

 11 11  0     0  0            999 V2000
   20.4078  -13.9394    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   21.2738  -13.4394    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   22.1398  -13.9394    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   23.0058  -13.4394    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   23.8720  -13.9394    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   24.7855  -13.5326    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   23.9766  -14.9340    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   25.4546  -14.2758    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   24.9548  -15.1418    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   24.9933  -12.5545    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   23.2334  -15.6031    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  2  1  1  0     0  0
  3  2  1  0     0  0
  4  3  1  0     0  0
  5  4  1  0     0  0
  6  5  1  0     0  0
  7  5  1  0     0  0
  8  6  1  0     0  0
  9  7  1  0     0  0
  9  8  2  0     0  0
  6 10  2  0     0  0
  7 11  2  0     0  0
M  STY  1   1 SRU
M  SLB  1   1   1
M  SCN  1   1 HT 
M  SMT   1 n
M  SAL   1  3   2   3   4
M  SBL   1  2   1   4
M  SDI   1  4   20.8408  -14.4394   20.8408  -12.9394
M  SDI   1  4   23.4389  -12.9394   23.4389  -14.4394
M  END
> <ID>
CHEBI:139326

> <NAME>
methoxypoly(ethylene glycol)-maleimide

> <DEFINITION>
A poly(ethylene glycol) derivative that is methoxypoly(ethylene glycol) in which the terminal hydroxy group has been converted to the corresponding 2-maleimidoethyl ether. Used particularly for the mPEGylation of free thiol groups in cysteine residues of proteins.

> <STAR>
3

> <SYNONYM>
mPEG-maleimide; mPEG-MAL; monomethoxypoly(ethylene glycol)-maleimide; mono-methyl poly(ethylene glycol) 2-maleimidoethyl ether; methoxy-polyethylene glycol maleimide

> <IUPAC_NAME>
alpha-methyl-omega-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)poly(oxyethylene)

> <FORMULA>
(C2H4O)n.C5H5NO2

> <CHARGE>
0

> <CAS_REGISTRY_NUMBER>
99126-64-4

> <REAXYS_REGISTRY_NUMBER>
15366089

> <PUBMED_CITATION>
23981355; 25667612; 25918947; 27355203; 28497240; 29053917

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