InChI=1S/C24H36O5/c1- 5- 15(3) 24(27) 29- 21- 11- 14(2) 10- 17- 7- 6- 16(4) 20(23(17) 21) 9- 8- 19- 12- 18(25) 13- 22(26) 28- 19/h6- 7,10,14- 16,18- 21,23,25H,5,8- 9,11- 13H2,1- 4H3/t14- ,15- ,16- ,18+,19+,20- ,21- ,23- /m0/s1 |
PCZOHLXUXFIOCF-BXMDZJJMSA-N |
[H][C@]12[C@H](C[C@@H](C)C=C1C=C[C@H](C)[C@@H]2CC[C@@H]1C[C@@H](O)CC(=O)O1)OC(=O)[C@@H](C)CC |
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Aspergillus metabolite
Any fungal metabolite produced during a metabolic reaction in the mould, Aspergillus .
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via statin (naturally occurring) )
EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor
Any EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD+ or NADP+ acceptor) inhibitor that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. The Enzyme Commission designation is EC 1.1.1.34 for the NADPH-dependent enzyme and EC 1.1.1.88 for an NADH-dependent enzyme.
(via statin )
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prodrug
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
anticholesteremic drug
A substance used to lower plasma cholesterol levels.
(via statin )
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
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View more via ChEBI Ontology
(1S,3R,7S,8S,8aR)- 8- {2- [(2R,4R)- 4- hydroxy- 6- oxotetrahydro- 2H- pyran- 2- yl]ethyl}- 3,7- dimethyl- 1,2,3,7,8,8a- hexahydronaphthalen- 1- yl (2S)- 2- methylbutanoate
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(1S,3R,7S,8S,8aR)- 1,2,3,7,8,8a- hexahydro- 3,7- dimethyl- 8- (2- (2R,4R)- (tetrahydro- 4- hydroxy- 6- oxo- 2H- pyran- 2- yl)ethyl)- 1- naphthalenyl (S)- 2- methyl- butyrate
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ChemIDplus
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2β,6α-dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactone
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ChemIDplus
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6α-methylcompactin
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ChemIDplus
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Lovastatin
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KEGG COMPOUND
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LOVASTATIN
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PDBeChem
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lovastatin
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UniProt
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Mevinolin
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ChemIDplus
|
MK-803
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KEGG DRUG
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ML-530B
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KEGG DRUG
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3631989
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Beilstein Registry Number
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ChemIDplus
|
4720754
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Reaxys Registry Number
|
Reaxys
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75330-75-5
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CAS Registry Number
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ChemIDplus
|
75330-75-5
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CAS Registry Number
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KEGG DRUG
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11375168
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PubMed citation
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Europe PMC
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11389707
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PubMed citation
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Europe PMC
|
11483865
|
PubMed citation
|
Europe PMC
|
18642339
|
PubMed citation
|
Europe PMC
|
24093797
|
PubMed citation
|
Europe PMC
|
7720768
|
PubMed citation
|
Europe PMC
|
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