CHEBI:134870 - toloxatone

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name toloxatone
ChEBI ID CHEBI:134870
Definition A racemate consisting of equimolar amounts of (R)- and (S)-toloxatone. It is a reversible monoamine oxidase A inhibitor and antidepressant.
Stars This entity has been manually annotated by the ChEBI Team.
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C11H13NO3
Net Charge 0
Average Mass 207.229
Monoisotopic Mass 207.08954
Roles Classification
Biological Role(s): EC 1.4.3.4 (monoamine oxidase) inhibitor
An EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of monoamine oxidase (EC 1.4.3.4).
Application(s): antidepressant
Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing toloxatone (CHEBI:134870) has part (R)-toloxatone (CHEBI:156573)
toloxatone (CHEBI:134870) has part (S)-toloxatone (CHEBI:156574)
toloxatone (CHEBI:134870) has role antidepressant (CHEBI:35469)
toloxatone (CHEBI:134870) has role EC 1.4.3.4 (monoamine oxidase) inhibitor (CHEBI:38623)
toloxatone (CHEBI:134870) is a racemate (CHEBI:60911)
IUPAC Name
rac-5-(hydroxymethyl)-3-(3-methylphenyl)-1,3-oxazolidin-2-one
INNs Sources
toloxatona WHO MedNet
toloxatone WHO MedNet
toloxatone WHO MedNet
toloxatonum WHO MedNet
Synonyms Sources
(5RS)-5-(hydroxymethyl)-3-(3-methylphenyl)-1,3-oxazolidin-2-one ChEBI
(RS)-toloxatone ChEBI
Delalande 69276 ChemIDplus
MD 69276 ChEBI
MD-69276 ChEBI
MD69276 ChEBI
rac-5-(hydroxymethyl)-3-(3-methylphenyl)-2-oxazolidinone ChEBI
rac-5-hydroxymethyl-3-(m-tolyl)-2-oxazolidinone ChEBI
rac-toloxatone ChEBI
racemic toloxatone ChEBI
Brand Names Sources
Humoryl KEGG DRUG
Perenum ChemIDplus
Manual Xrefs Databases
2702 DrugCentral
D02559 KEGG DRUG
DB09245 DrugBank
Toloxatone Wikipedia
US4699782 Patent
View more database links
Registry Numbers Types Sources
29218-27-7 CAS Registry Number ChemIDplus
527506 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
10371410 PubMed citation Europe PMC
1221563 PubMed citation Europe PMC
12659549 PubMed citation Europe PMC
1352813 PubMed citation Europe PMC
1424410 PubMed citation Europe PMC
1546124 PubMed citation Europe PMC
1546145 PubMed citation Europe PMC
1705137 PubMed citation Europe PMC
1843597 PubMed citation Europe PMC
2353326 PubMed citation Europe PMC
2365178 PubMed citation Europe PMC
2768411 PubMed citation Europe PMC
29844717 PubMed citation Europe PMC
32935716 PubMed citation Europe PMC
3634492 PubMed citation Europe PMC
3810545 PubMed citation Europe PMC
409416 PubMed citation Europe PMC
41906 PubMed citation Europe PMC
494659 PubMed citation Europe PMC
551645 PubMed citation Europe PMC
6520180 PubMed citation Europe PMC
6633672 PubMed citation Europe PMC
7200786 PubMed citation Europe PMC
7884022 PubMed citation Europe PMC
8094790 PubMed citation Europe PMC
8436164 PubMed citation Europe PMC
Last Modified
02 октября 2020