CHEBI:9011 - salmeterol

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ChEBI Name salmeterol ChEBI ID CHEBI:9011 Definition A racemate consisting of equal parts of (R)- and (S)-salmeterol. It is a potent and selective β2-adrenoceptor agonist (EC50 = 5.3 nM). Unlike other β2 agonists, it binds to the exo-site domain of β2 receptors, producing a slow onset of action and prolonged activation. Stars This entity has been manually annotated by the ChEBI Team. Wikipedia License Read full article at Wikipedia Formula C25H37NO4 Net Charge 0 Average Mass 415.56560 Monoisotopic Mass 415.27226 Roles Classification Biological Role(s): beta-adrenergic agonist An agent that selectively binds to and activates beta-adrenergic receptors. Application(s): bronchodilator agent An agent that causes an increase in the expansion of a bronchus or bronchial tubes. beta-adrenergic agonist An agent that selectively binds to and activates beta-adrenergic receptors. View more via ChEBI Ontology ChEBI Ontology Outgoing salmeterol (CHEBI:9011) has part (R)-salmeterol (CHEBI:64062) salmeterol (CHEBI:9011) has part (S)-salmeterol (CHEBI:64063) salmeterol (CHEBI:9011) has role β-adrenergic agonist (CHEBI:35522) salmeterol (CHEBI:9011) has role bronchodilator agent (CHEBI:35523) salmeterol (CHEBI:9011) is a racemate (CHEBI:60911) INNs Sources salmeterol ChemIDplus salmétérol WHO MedNet salmeterol WHO MedNet salmeterolum ChemIDplus Synonyms Sources (±)-4-hydroxy-α1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-m-xylene-α,α1-diol ChEBI (±)-salmeterol ChEBI (RS)-4-hydroxy-α1-({[6-(4-phenylbutoxy)hexyl]amino}methyl)-1,3-benzenedimethanol ChEBI (RS)-salmeterol ChEBI Salmeterol KEGG COMPOUND Manual Xrefs Databases C07241 KEGG COMPOUND D05792 KEGG DRUG DB00938 DrugBank DE3414752 Patent HMDB0015073 HMDB Salmeterol Wikipedia US4992474 Patent View more database links Registry Number Type Source 89365-50-4 CAS Registry Number ChemIDplus Citations Types Sources 22192967 PubMed citation Europe PMC 22231554 PubMed citation Europe PMC 22235841 PubMed citation Europe PMC 22245487 PubMed citation Europe PMC Last Modified 22 February 2017

General Comment 2014-05-01 It can be found in blood and urine samples of individuals who have taken this drug.