InChI=1S/C28H32N4O3/c1-2-13-32(12-1)14-17-35-27-9-8-25-19-24(27)21-34-16-4-3-15-33-20-22-6-5-7-23(18-22)26-10-11-29-28(30-25)31-26/h3-11,18-19H,1-2,12-17,20-21H2,(H,29,30,31)/b4-3+ |
HWXVIOGONBBTBY-ONEGZZNKSA-N |
C(CN1CCCC1)OC1=C2COC\C=C\COCC3=CC=CC(=C3)C3=CC=NC(NC(C=C1)=C2)=N3 |
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EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that specifically blocks the action of non-specific protein-tyrosine kinase (EC 2.7.10.2).
apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
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antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
anti-inflammatory agent
Any compound that has anti-inflammatory effects.
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View more via ChEBI Ontology
(16E)-11-[2-(pyrrolidin-1-yl)ethoxy]-14,19-dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(25),2(27),3,5,8(26),9,11,16,21,23-decaene
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pacritinib
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WHO MedNet
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pacritinib
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WHO MedNet
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pacritinib
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WHO MedNet
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pacritinibum
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WHO MedNet
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(16E)-11-[2-(1-pyrrolidinyl)ethoxy]-14,19-dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(25),2,4,6(27),8,10,12(26),16,21,23-decaene
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ChEBI
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SB 1518
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DrugBank
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SB-1518
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DrugBank
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SB1518
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DrugBank
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937272-79-2
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CAS Registry Number
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KEGG DRUG
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21604762
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PubMed citation
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Europe PMC
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25170285
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PubMed citation
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Europe PMC
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27598824
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PubMed citation
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Europe PMC
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29191878
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PubMed citation
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Europe PMC
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34551507
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Europe PMC
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35489775
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Europe PMC
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35567653
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PubMed citation
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Europe PMC
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35622972
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PubMed citation
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Europe PMC
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35877951
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PubMed citation
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Europe PMC
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35983661
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PubMed citation
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Europe PMC
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35993369
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PubMed citation
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Europe PMC
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36467816
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PubMed citation
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Europe PMC
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36469321
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Europe PMC
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36601980
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Europe PMC
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36651066
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Europe PMC
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36697489
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Europe PMC
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36822800
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Europe PMC
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36861402
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Europe PMC
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36922391
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Europe PMC
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36959157
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Europe PMC
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37203407
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Europe PMC
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37427653
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Europe PMC
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37552106
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Europe PMC
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37916436
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Europe PMC
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38164985
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Europe PMC
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38201581
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Europe PMC
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38295318
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Europe PMC
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38374336
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Europe PMC
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38562076
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Europe PMC
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38646919
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