CHEBI:142773 - estetrol

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name estetrol
ChEBI ID CHEBI:142773
Definition A 3-hydroxy steroid that is 17β-estradiol which has been substituted at the 15α and 16α positions by two additional hydroxy groups. It is a natural estrogen produced exclusively during pregnancy by the fetal liver.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Peter D'Eustachio
Supplier Information
Download Molfile XML SDF
Roles Classification
Biological Role(s): estrogen
A hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens.
estrogen receptor agonist
An agonist at the estrogen receptor.
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
human xenobiotic metabolite
Any human metabolite produced by metabolism of a xenobiotic compound in humans.
hormone
Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
(via steroid hormone )
Application(s): oral contraceptive
A compound, usually hormonal, taken orally in order to block ovulation and prevent the occurrence of pregnancy.
Related Structures
estetrol is a Structural Derivative of
estrane
Mass : 246.43080
Formula : C18H30
23966
Graph View Tree View
Relationship Types
is a
has part
is conjugate base of
is conjugate acid of
is tautomer of
is enantiomer of
has functional parent
has parent hydride
is substituent group from
has role
Status
Checked
Unchecked